Preheat oven to 350 degrees.In a large bowl, sift together the dry ingredients for the meatballs: panko breadcrumbs, smoked paprika*, chili powder, garlic powder, salt, and pepper.Add the ground pork and beef to the bowl. Using your hands, kneed the meat into the dry ingredients until thoroughly combined.Use a small ice cream scoop (or just continue to use your hands) to create meatballs that are 1 inch in size. Roll each one in your hand for 5-10 seconds to ensure the balls are even and keep their shape.Place rolled meatballs on a large baking sheet. It's okay if they are packed tightly. Bake for 15-20 minutes.Add all of the Metaxa sauce ingredients into a large saucepan: ketchup, Metaxa, brown sugar, apple cider vinegar, spicy brown mustard, honey, garlic powder, smoked paprika*, chili powder, and salt. Whisk ingredients together.Cover and let simmer on medium-low heat for 15-20 minutes.Remove meatballs from the oven and gently add them to the pot with the Metaxa sauce. Coat meatballs with sauce, then cover and let simmer for another 5-10 minutes on medium-low heat.Serve immediately.